Prostate Patient Case Studies

Prostate Patient Case Studies-10
In addition to radiotherapy Vic received an androgen deprivation (AD) drug called Lucrin in a clinical trial known as RADAR (Randomised Androgen Deprivation and Radiotherapy).By inhibiting testosterone levels it shrinks the prostate and thus also shrinks the prostate cancer tissue. Carlos Aquino, a 63 year old Filipino male with hormone-refractory prostate cancer is your clinic patient. Aquino was diagnosed with benign prostatic hypertrophy (BPH) several years ago and was taking alpha blockers for this condition.

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He realizes that despite his young age, metastatic prostate cancer is an uncurable disease with treatments being primarily palliative with rather modest survival benefit at the current stage.

Though his wishes are to continue considering available chemotherapy/radiation, Mr.

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At that time you performed a digital rectal exam and noted that he had a new hard nodule (1cm x 1cm) in the right lobe of his prostate and a PSA of 2.4 (PSA in the year prior to that was 2.2).

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A prostate biopsy revealed high-grade adenocarcinoma in 5/5 R lobe biopsy specimens with Gleason’s score of 4 5, and 2/5 of L lobe biopsies.

As one would expect, compared to localized prostate cancer, metastatic disease remains the more challenging type to treat.

In 1941 Huggins and Hodges demonstrated the dependence of prostatic tissues on androgens and from this work hormonal therapy was developed as the primary treatment for metastatic prostate cancer.

Aquino’s primary goal is to be pain free, and to be able to spend quality time with his family, and to stay active.

Though he would prefer to have CPR and intubation as treatments for acute issues, he would not like prolonged life support and would wish to have them withdrawn if they only served to prolong his life artificially. Richard Scott, Professor Emeritus in the Department of Sociology, shares a very personal story of the last stages of life of his beloved brother Charles Scott.


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